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Antifungal and antibacterial functions of medicinal leech recombinant destabilase-lysozyme and its heated-up derivative

T. G. YUDINA, Danyang GUO, N. F. PISKUNKOVA, I. B. PAVLOVA, L. L. ZAVALOVA, I. P. BASKOVA

Frontiers of Chemical Science and Engineering 2012, Volume 6, Issue 2, Pages 203-209 doi: 10.1007/s11705-012-1277-2

Abstract: Antifungal activity of recombinant medicinal leech destabilase-lysozyme (rec.Dest-Lys) was investigatedMuramidase activity of rec.Dest-Lys disappeared after heat-treating at 90°C for 50 min without the lossFurthermore we showed for the first time that the heated-up derivative of rec.Dest-Lys exhibited more

Keywords： recombinant destabilase-lysozyme (rec.Dest-Lys) antimicrobial activity antifungal activity medicinalleech heated-up derivative of rec.Dest-Lys (T-rec.Dest-Lys)